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style="white-space: normal; list-style: none; margin: 0px; padding: 0px; outline: 0px; border: 0px currentcolor; line-height: 28.8px; font-family: 微软雅黑; vertical-align: baseline; background-color: rgb(255, 255, 255);"><span style="list-style: none; margin: 0px; padding: 0px; outline: 0px; border: 0px currentcolor; font-size: larger; vertical-align: baseline;"><strong style="list-style: none; margin: 0px; padding: 0px; outline: 0px; border: 0px currentcolor; font-size: 19.2px; vertical-align: baseline;"></strong></span></p><table><tbody><tr class="firstRow"><td width="75" style="border-top-width: 1px; border-top-color: rgb(237, 125, 49); border-bottom: 1px solid rgb(237, 125, 49); border-left-width: initial; border-left-color: initial; border-image: initial; border-right: none; background: rgb(237, 125, 49); padding: 0px 7px;"><p style="text-align:center"><strong><span style=";font-family:'微软雅黑',sans-serif;color:black">服务序号</span></strong></p></td><td width="255" style="border-top-width: 1px; border-top-color: rgb(237, 125, 49); border-left-width: initial; border-left-color: initial; border-bottom: 1px solid rgb(237, 125, 49); border-right: none; background: rgb(237, 125, 49); padding: 0px 7px;"><p style="text-align:center"><strong><span style=";font-family:'微软雅黑',sans-serif;color:black">服务内容</span></strong></p></td><td width="510" style="border-top-width: 1px; border-top-color: rgb(237, 125, 49); border-left-width: initial; border-left-color: initial; border-bottom: 1px solid rgb(237, 125, 49); border-right: none; background: rgb(237, 125, 49); padding: 0px 7px;"><p style="text-align:center"><strong><span style=";font-family:'微软雅黑',sans-serif;color:black">服务说明</span></strong></p></td><td width="142" style="border-top-width: 1px; border-top-color: rgb(237, 125, 49); border-left-width: initial; border-left-color: initial; border-bottom: 1px solid rgb(237, 125, 49); border-right: none; background: rgb(237, 125, 49); padding: 0px 7px;"><p style="text-align:center"><strong><span style=";font-family:'微软雅黑',sans-serif;color:black">收费标准</span></strong></p></td><td width="142" style="border-width: 1px; border-color: rgb(237, 125, 49); border-right-style: solid; border-bottom-style: solid; border-image: initial; background: rgb(237, 125, 49); padding: 0px 7px;"><p style="text-align:center"><strong><span style=";font-family:'微软雅黑',sans-serif;color:black">服务周期</span></strong></p></td></tr><tr><td width="75" style="border-width: 1px; border-right-style: solid; border-color: rgb(244, 176, 131); border-bottom-style: solid; border-image: initial; background: rgb(251, 228, 213); padding: 0px 7px;"><p style="text-align:center"><span style=";font-family:'微软雅黑',sans-serif;color:black">1</span></p></td><td width="255" style="border-width: 1px; border-color: rgb(244, 176, 131); border-bottom-style: solid; border-right-style: solid; background: rgb(251, 228, 213); padding: 0px 7px;"><p style="text-align:center"><span style="color:black">外源装载（转染）</span></p></td><td width="510" style="border-width: 1px; border-color: rgb(244, 176, 131); border-bottom-style: solid; border-right-style: solid; background: rgb(251, 228, 213); padding: 0px 7px;"><p style="text-align:center"><span style="color:black">采用阳离子物质促进与脂质膜的相互作用和随后的内在化，可有效将核酸加载到 外泌体内部</span></p></td><td width="142" style="border-width: 1px; border-color: rgb(244, 176, 131); border-bottom-style: solid; border-right-style: solid; background: rgb(251, 228, 213); padding: 0px 7px;"><p style="text-align:center"><span style="color:black">1000</span><span style="color:black">元/样</span></p></td><td width="142" style="border-width: 1px; border-color: rgb(244, 176, 131); border-bottom-style: solid; border-right-style: solid; background: rgb(251, 228, 213); padding: 0px 7px;"><p style="text-align:center"><span style="color:black">3</span><span style="color:black">个工作日</span></p></td></tr><tr><td width="75" style="border-width: 1px; border-right-style: solid; border-color: rgb(244, 176, 131); border-bottom-style: solid; border-image: initial; padding: 0px 7px;"><p style="text-align:center"><span style=";font-family:'微软雅黑',sans-serif;color:black">2</span></p></td><td width="255" style="border-width: 1px; border-color: rgb(244, 176, 131); border-bottom-style: solid; border-right-style: solid; padding: 0px 7px;"><p style="text-align:center">外源装载（超声）</p></td><td width="510" style="border-width: 1px; border-color: rgb(244, 176, 131); border-bottom-style: solid; border-right-style: solid; padding: 0px 7px;"><p style="text-align:center">采用探针超声仪对外泌体进行超声处理，增加膜的通透性，使小分子物质扩散到外泌体中</p></td><td width="142" style="border-width: 1px; border-color: rgb(244, 176, 131); border-bottom-style: solid; border-right-style: solid; padding: 0px 7px;"><p style="text-align:center">500元/样</p></td><td width="142" style="border-width: 1px; border-color: rgb(244, 176, 131); border-bottom-style: solid; border-right-style: solid; padding: 0px 7px;"><p style="text-align:center">3个工作日</p></td></tr><tr><td width="75" style="border-width: 1px; border-right-style: solid; border-color: rgb(244, 176, 131); border-bottom-style: solid; border-image: initial; background: rgb(251, 228, 213); padding: 0px 7px;"><p style="text-align:center"><span style=";font-family:'微软雅黑',sans-serif;color:black">3</span></p></td><td width="255" style="border-width: 1px; border-color: rgb(244, 176, 131); border-bottom-style: solid; border-right-style: solid; background: rgb(251, 228, 213); padding: 0px 7px;"><p style="text-align:center"><span style="color:black">外源装载（脂锚）</span></p></td><td width="510" style="border-width: 1px; border-color: rgb(244, 176, 131); border-bottom-style: solid; border-right-style: solid; background: rgb(251, 228, 213); padding: 0px 7px;"><p style="text-align:center"><span style="color:black">采用DSPE-PEG分子锚定到外泌体膜上，将所连接的靶向分子或功能分子锚定至外泌体表面</span></p></td><td width="142" style="border-width: 1px; border-color: rgb(244, 176, 131); border-bottom-style: solid; border-right-style: solid; background: rgb(251, 228, 213); padding: 0px 7px;"><p style="text-align:center"><span style="color:black">500</span><span style="color:black">元/样</span></p></td><td width="142" style="border-width: 1px; border-color: rgb(244, 176, 131); border-bottom-style: solid; border-right-style: solid; background: rgb(251, 228, 213); padding: 0px 7px;"><p style="text-align:center"><span style="color:black">3</span><span style="color:black">个工作日</span></p></td></tr><tr><td width="75" style="border-width: 1px; border-right-style: solid; border-color: rgb(244, 176, 131); border-bottom-style: solid; border-image: initial; padding: 0px 7px;"><p style="text-align:center"><span style=";font-family:'微软雅黑',sans-serif;color:black">4</span></p></td><td width="255" style="border-width: 1px; border-color: rgb(244, 176, 131); border-bottom-style: solid; border-right-style: solid; padding: 0px 7px;"><p style="text-align:center">外源装载（偶联）</p></td><td width="510" style="border-width: 1px; border-color: rgb(244, 176, 131); border-bottom-style: solid; border-right-style: solid; padding: 0px 7px;"><p style="text-align:center">采用噬菌体库筛选肽可特异性结合CD63的特性，将靶向分子或功能分子偶联至外泌体表面，实现靶向性或功能性</p></td><td width="142" style="border-width: 1px; border-color: rgb(244, 176, 131); border-bottom-style: solid; border-right-style: solid; padding: 0px 7px;"><p style="text-align:center">500元/样</p></td><td width="142" style="border-width: 1px; border-color: rgb(244, 176, 131); border-bottom-style: solid; border-right-style: solid; padding: 0px 7px;"><p style="text-align:center">3个工作日</p></td></tr><tr><td width="75" style="border-width: 1px; border-right-style: solid; border-color: rgb(244, 176, 131); border-bottom-style: solid; border-image: initial; background: rgb(251, 228, 213); padding: 0px 7px;"><p style="text-align:center"><span style=";font-family:'微软雅黑',sans-serif;color:black">5</span></p></td><td width="255" style="border-width: 1px; border-color: rgb(244, 176, 131); border-bottom-style: solid; border-right-style: solid; background: rgb(251, 228, 213); padding: 0px 7px;"><p style="text-align:center"><span style="color:black">外源装载（点击化学）</span></p></td><td width="510" style="border-width: 1px; border-color: rgb(244, 176, 131); border-bottom-style: solid; border-right-style: solid; background: rgb(251, 228, 213); padding: 0px 7px;"><p style="text-align:center"><span style="color:black">采用点击化学修饰的方法，将靶向分子或功能分子偶联至外泌体表面，实现靶向性或功能性</span></p></td><td width="142" style="border-width: 1px; border-color: rgb(244, 176, 131); border-bottom-style: solid; border-right-style: solid; background: rgb(251, 228, 213); padding: 0px 7px;"><p style="text-align:center"><span style="color:black">2000</span><span style="color:black">元/样</span></p></td><td width="142" style="border-width: 1px; border-color: rgb(244, 176, 131); border-bottom-style: solid; border-right-style: solid; background: rgb(251, 228, 213); padding: 0px 7px;"><p style="text-align:center"><span style="color:black">10</span><span style="color:black">个工作日</span></p></td></tr><tr><td width="75" style="border-width: 1px; border-right-style: solid; border-color: rgb(244, 176, 131); border-bottom-style: solid; border-image: initial; padding: 0px 7px;"><p style="text-align:center"><span style=";font-family:'微软雅黑',sans-serif;color:black">6</span></p></td><td width="255" style="border-width: 1px; border-color: rgb(244, 176, 131); border-bottom-style: solid; border-right-style: solid; padding: 0px 7px;"><p style="text-align:center">内源装载（基因干扰）</p></td><td width="510" style="border-width: 1px; border-color: rgb(244, 176, 131); border-bottom-style: solid; border-right-style: solid; padding: 0px 7px;"><p style="text-align:center">采用转染质粒或转导病毒的方法，使亲代细胞降低目标核酸或蛋白的表达，最终影响外泌体的目标分子表达</p></td><td width="142" style="border-width: 1px; border-color: rgb(244, 176, 131); border-bottom-style: solid; border-right-style: solid; padding: 0px 7px;"><p style="text-align:center">2000元/样</p></td><td width="142" style="border-width: 1px; border-color: rgb(244, 176, 131); border-bottom-style: solid; border-right-style: solid; padding: 0px 7px;"><p style="text-align:center">25个工作日</p></td></tr><tr><td width="75" style="border-width: 1px; border-right-style: solid; border-color: rgb(244, 176, 131); border-bottom-style: solid; border-image: initial; background: rgb(251, 228, 213); padding: 0px 7px;"><p style="text-align:center"><span style=";font-family:'微软雅黑',sans-serif;color:black">7</span></p></td><td width="255" style="border-width: 1px; border-color: rgb(244, 176, 131); border-bottom-style: solid; border-right-style: solid; background: rgb(251, 228, 213); padding: 0px 7px;"><p style="text-align:center"><span style="color:black">内源装载（基因过表达）</span></p></td><td width="510" style="border-width: 1px; border-color: rgb(244, 176, 131); border-bottom-style: solid; border-right-style: solid; background: rgb(251, 228, 213); padding: 0px 7px;"><p style="text-align:center"><span style="color:black">采用转染质粒或转导病毒的方法，使亲代细胞提高目标核酸或蛋白的表达，最终影响外泌体的目标分子表达</span></p></td><td width="142" style="border-width: 1px; border-color: rgb(244, 176, 131); border-bottom-style: solid; border-right-style: solid; background: rgb(251, 228, 213); padding: 0px 7px;"><p style="text-align:center"><span style="color:black">4000</span><span style="color:black">元/样</span></p></td><td width="142" style="border-width: 1px; border-color: rgb(244, 176, 131); border-bottom-style: solid; border-right-style: solid; background: rgb(251, 228, 213); padding: 0px 7px;"><p style="text-align:center"><span style="color:black">25</span><span style="color:black">个工作日</span></p></td></tr><tr><td width="75" style="border-width: 1px; border-right-style: solid; border-color: rgb(244, 176, 131); border-bottom-style: solid; border-image: initial; padding: 0px 7px;"><p style="text-align:center"><span style=";font-family:'微软雅黑',sans-serif;color:black">8</span></p></td><td width="255" style="border-width: 1px; border-color: rgb(244, 176, 131); border-bottom-style: solid; border-right-style: solid; padding: 0px 7px;"><p style="text-align:center">载药浓度检测（HPLC）</p></td><td width="510" style="border-width: 1px; border-color: rgb(244, 176, 131); border-bottom-style: solid; border-right-style: solid; padding: 0px 7px;"><p style="text-align:center">采用高效液相色谱HPLC的方法检测外泌体载药效率</p></td><td width="142" style="border-width: 1px; border-color: rgb(244, 176, 131); border-bottom-style: solid; border-right-style: solid; padding: 0px 7px;"><p style="text-align:center">1000元/样</p></td><td width="142" style="border-width: 1px; border-color: rgb(244, 176, 131); border-bottom-style: solid; border-right-style: solid; padding: 0px 7px;"><p style="text-align:center">10个工作日</p></td></tr><tr><td width="75" style="border-width: 1px; border-right-style: solid; border-color: rgb(244, 176, 131); border-bottom-style: solid; border-image: initial; background: rgb(251, 228, 213); padding: 0px 7px;"><p style="text-align:center"><span style=";font-family:'微软雅黑',sans-serif;color:black">9</span></p></td><td width="255" style="border-width: 1px; border-color: rgb(244, 176, 131); border-bottom-style: solid; border-right-style: solid; background: rgb(251, 228, 213); padding: 0px 7px;"><p style="text-align:center"><span style="color:black">载药浓度检测（LC-MS）</span></p></td><td width="510" style="border-width: 1px; border-color: rgb(244, 176, 131); border-bottom-style: solid; border-right-style: solid; background: rgb(251, 228, 213); padding: 0px 7px;"><p style="text-align:center"><span style="color:black">采用液质谱联用LC-MS的方法检测外泌体载药效率</span></p></td><td width="142" style="border-width: 1px; border-color: rgb(244, 176, 131); border-bottom-style: solid; border-right-style: solid; background: rgb(251, 228, 213); padding: 0px 7px;"><p style="text-align:center"><span style="color:black">1500</span><span style="color:black">元/样</span></p></td><td width="142" style="border-width: 1px; border-color: rgb(244, 176, 131); border-bottom-style: solid; border-right-style: solid; background: rgb(251, 228, 213); padding: 0px 7px;"><p style="text-align:center"><span style="color:black">10</span><span style="color:black">个工作日</span></p></td></tr></tbody></table><p style="white-space: normal; list-style: none; margin: 0px; padding: 0px; outline: 0px; border: 0px currentcolor; line-height: 28.8px; font-family: 微软雅黑; vertical-align: baseline; background-color: rgb(255, 255, 255);"><br/></p><div style="white-space: normal; list-style: none; margin: 0px; padding: 0px; outline: 0px; border: 0px currentcolor; line-height: 28.8px; font-family: 微软雅黑; vertical-align: baseline; background-color: rgb(255, 255, 255);"><span style="list-style: none; margin: 0px; padding: 0px; outline: 0px; border: 0px currentcolor; font-size: larger; vertical-align: baseline;"><strong style="list-style: none; margin: 0px; padding: 0px; outline: 0px; border: 0px currentcolor; font-size: 19.2px; vertical-align: baseline;">实验介绍</strong></span></div><p style="white-space: normal;"> <span style="font-family: 微软雅黑, "Microsoft YaHei";"> </span></p><p> 外泌体修饰改造是指通过改变外泌体的表面分子结构或在外泌体内部添加新的生物分子，从而增强外泌体的定向输送和靶向治疗效果。外泌体修饰改造可以为研究人员提供更有效的外泌体治疗方案。外泌体修饰改造技术服务项目通常包括外泌体的提取、修饰或改造、外泌体的纯化和检测等多个环节。通过这些环节，研究人员可以获得经过修饰或改造的外泌体，并对其进行纯化和检测，进而实现外泌体的定向输送和靶向治疗。</p><p style="text-align: center;"><img src="/upload/images/202305/16849154177549.jpg" title="16849154177549.jpg" alt="55.jpg"/></p><p style="text-align: center;"><img src="/upload/images/202305/16849126937508.jpg" title="16849126937508.jpg" alt="50.jpg"/></p><p><br/></p></div> <div class="blank30"></div> <div class="blank30"></div> <!--自动调用自定义字段--> <div class="blank20"></div> <div class="blank30"></div> <!-- 投票 --> <script src="/index.php?case=vote&act=view&aid=286"></script> <!-- 自定义表单开始 --> <!-- 自定义表单结束 --> <div class="blank60"></div> <!-- 上下页开始 --> <div id="page"> <strong>上一篇</strong><a href="show_284.htm">分选加工</a> <div class="blank10"></div> 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