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<!--用于打印和文字放大--> <div class="content_tools_box"> <p class="content_tools"> <a href="javascript:CallPrint('print');">打印本文</a> <a href="javascript:doZoom(14)">小</a> <a href="javascript:doZoom(18)">中</a> <a href="javascript:doZoom(20)">大</a> </p> <div class="clearfix"></div> <script src="/template/D20170425/skin/js/c_tool.js" type="text/javascript" ></script> </div> <!--/用于打印和文字放大--> <!-- 正文 --> <div class="lead content" id="print"> <div style="white-space: normal; list-style: none; margin: 0px; padding: 0px; outline: 0px; border: 0px currentcolor; line-height: 28.8px; font-family: 微软雅黑; vertical-align: baseline; background-color: rgb(255, 255, 255);"><span style="list-style: none; margin: 0px; padding: 0px; outline: 0px; border: 0px currentcolor; font-size: larger; vertical-align: baseline;"><strong style="list-style: none; margin: 0px; padding: 0px; outline: 0px; border: 0px currentcolor; font-size: 19.2px; vertical-align: baseline;">实验介绍</strong></span></div><p style="white-space: normal;"> <span style="font-family: 微软雅黑, "Microsoft YaHei";"> </span></p><p> 外泌体修饰改造是指通过改变外泌体的表面分子结构或在外泌体内部添加新的生物分子，从而增强外泌体的定向输送和靶向治疗效果。外泌体修饰改造可以为研究人员提供更有效的外泌体治疗方案。外泌体修饰改造技术服务项目通常包括外泌体的提取、修饰或改造、外泌体的纯化和检测等多个环节。通过这些环节，研究人员可以获得经过修饰或改造的外泌体，并对其进行纯化和检测，进而实现外泌体的定向输送和靶向治疗。</p><p style="text-align: center;"><img src="/upload/images/202305/16849154177549.jpg" title="16849154177549.jpg" alt="55.jpg"/></p><p style="text-align: center;"><img src="/upload/images/202305/16849126937508.jpg" title="16849126937508.jpg" alt="50.jpg"/></p><p><strong style="font-family: 微软雅黑; font-size: 19.2px; text-wrap: wrap; background-color: rgb(255, 255, 255); list-style: none; margin: 0px; padding: 0px; outline: 0px; border: 0px currentcolor; vertical-align: baseline;">检测项目</strong></p><p><strong style="font-family: 微软雅黑; font-size: 19.2px; text-wrap: wrap; background-color: rgb(255, 255, 255); list-style: none; margin: 0px; padding: 0px; outline: 0px; border: 0px currentcolor; vertical-align: baseline;"><br/></strong></p><table cellspacing="0" cellpadding="0" width="1105" align="center"><tbody><tr class="firstRow"><td width="103" style="border-top: 1px solid rgb(237, 125, 49); border-bottom: 1px solid rgb(237, 125, 49); border-left: 1px solid rgb(237, 125, 49); border-image: initial; border-right: none; background: rgb(237, 125, 49); padding: 0px 7px;"><p style="text-align:center"><strong><span style=";font-family:'微软雅黑',sans-serif;color:black">服务序号</span></strong></p></td><td width="255" style="border-top: 1px solid rgb(237, 125, 49); border-left: none; border-bottom: 1px solid rgb(237, 125, 49); border-right: none; background: rgb(237, 125, 49); padding: 0px 7px;"><p style="text-align:center"><strong><span style=";font-family:'微软雅黑',sans-serif;color:black">服务内容</span></strong></p></td><td width="558" style="border-top: 1px solid rgb(237, 125, 49); border-left: none; border-bottom: 1px solid rgb(237, 125, 49); border-right: none; background: rgb(237, 125, 49); padding: 0px 7px;"><p style="text-align:center"><strong><span style=";font-family:'微软雅黑',sans-serif;color:black">服务说明</span></strong></p></td><td width="125" style="border-top: 1px solid rgb(237, 125, 49); border-right: 1px solid rgb(237, 125, 49); border-bottom: 1px solid rgb(237, 125, 49); border-image: initial; border-left: none; background: rgb(237, 125, 49); padding: 0px 7px;"><p style="text-align:center"><strong><span style=";font-family:'微软雅黑',sans-serif;color:black">服务周期</span></strong></p></td></tr><tr><td width="103" style="border-right: 1px solid rgb(244, 176, 131); border-bottom: 1px solid rgb(244, 176, 131); border-left: 1px solid rgb(244, 176, 131); border-image: initial; border-top: none; background: rgb(251, 228, 213); padding: 0px 7px;"><p style="text-align:center"><span style=";font-family:'微软雅黑',sans-serif;color:black">1</span></p></td><td width="255" style="border-top: none; border-left: none; border-bottom: 1px solid rgb(244, 176, 131); border-right: 1px solid rgb(244, 176, 131); background: rgb(251, 228, 213); padding: 0px 7px;"><p style="text-align:center"><span style=";font-family:'微软雅黑',sans-serif;color:black">药物装载（超声转染）</span></p></td><td width="558" style="border-top: none; border-left: none; border-bottom: 1px solid rgb(244, 176, 131); border-right: 1px solid rgb(244, 176, 131); background: rgb(251, 228, 213); padding: 0px 7px;"><p style="text-align:center"><span style=";font-family:'微软雅黑',sans-serif;color:black">利用探针超声仪对外泌体进行超声处理，增加膜的通透性，使小分子物质扩散到外泌体中，交付：载药外泌体及参数检测报告</span></p></td><td width="125" style="border-top: none; border-left: none; border-bottom: 1px solid rgb(244, 176, 131); border-right: 1px solid rgb(244, 176, 131); background: rgb(251, 228, 213); padding: 0px 7px;"><p style="text-align:center"><span style=";font-family:'微软雅黑',sans-serif;color:black">3</span><span style=";font-family:'微软雅黑',sans-serif;color:black">个工作日</span></p></td></tr><tr><td width="103" style="border-right: 1px solid rgb(244, 176, 131); border-bottom: 1px solid rgb(244, 176, 131); border-left: 1px solid rgb(244, 176, 131); border-image: initial; border-top: none; padding: 0px 7px;"><p style="text-align:center"><span style=";font-family:'微软雅黑',sans-serif;color:black">2</span></p></td><td width="255" style="border-top: none; border-left: none; border-bottom: 1px solid rgb(244, 176, 131); border-right: 1px solid rgb(244, 176, 131); padding: 0px 7px;"><p style="text-align:center"><span style=";font-family:'微软雅黑',sans-serif;color:black">药物装载（试剂转染）</span></p></td><td width="558" style="border-top: none; border-left: none; border-bottom: 1px solid rgb(244, 176, 131); border-right: 1px solid rgb(244, 176, 131); padding: 0px 7px;"><p style="text-align:center"><span style=";font-family:'微软雅黑',sans-serif;color:black">利用阳离子物质促进与脂质膜的相互作用和随后的内在化，可有效将核酸加载到 外泌体内部，交付：载药外泌体及参数检测报告</span></p></td><td width="125" style="border-top: none; border-left: none; border-bottom: 1px solid rgb(244, 176, 131); border-right: 1px solid rgb(244, 176, 131); padding: 0px 7px;"><p style="text-align:center"><span style=";font-family:'微软雅黑',sans-serif;color:black">3</span><span style=";font-family:'微软雅黑',sans-serif;color:black">个工作日</span></p></td></tr><tr><td width="103" style="border-right: 1px solid rgb(244, 176, 131); border-bottom: 1px solid rgb(244, 176, 131); border-left: 1px solid rgb(244, 176, 131); border-image: initial; border-top: none; background: rgb(251, 228, 213); padding: 0px 7px;"><p style="text-align:center"><span style=";font-family:'微软雅黑',sans-serif;color:black">3</span></p></td><td width="255" style="border-top: none; border-left: none; border-bottom: 1px solid rgb(244, 176, 131); border-right: 1px solid rgb(244, 176, 131); background: rgb(251, 228, 213); padding: 0px 7px;"><p style="text-align:center"><span style=";font-family:'微软雅黑',sans-serif;color:black">药物装载（电穿孔转染）</span></p></td><td width="558" style="border-top: none; border-left: none; border-bottom: 1px solid rgb(244, 176, 131); border-right: 1px solid rgb(244, 176, 131); background: rgb(251, 228, 213); padding: 0px 7px;"><p style="text-align:center"><span style=";font-family:'微软雅黑',sans-serif;color:black">外加电场使外泌体膜上形成临时的亲水性孔道，增加膜的通透性，使小分子物质能够穿过孔道进入外泌体内部，交付：载药外泌体及参数检测报告</span></p></td><td width="125" style="border-top: none; border-left: none; border-bottom: 1px solid rgb(244, 176, 131); border-right: 1px solid rgb(244, 176, 131); background: rgb(251, 228, 213); padding: 0px 7px;"><p style="text-align:center"><span style=";font-family:'微软雅黑',sans-serif;color:black">7</span><span style=";font-family:'微软雅黑',sans-serif;color:black">个工作日</span></p></td></tr><tr><td width="103" style="border-right: 1px solid rgb(244, 176, 131); border-bottom: 1px solid rgb(244, 176, 131); border-left: 1px solid rgb(244, 176, 131); border-image: initial; border-top: none; padding: 0px 7px;"><p style="text-align:center"><span style=";font-family:'微软雅黑',sans-serif;color:black">4</span></p></td><td width="255" style="border-top: none; border-left: none; border-bottom: 1px solid rgb(244, 176, 131); border-right: 1px solid rgb(244, 176, 131); padding: 0px 7px;"><p style="text-align:center"><span style=";font-family:'微软雅黑',sans-serif;color:black">药物装载（噬菌体肽偶联）</span></p></td><td width="558" style="border-top: none; border-left: none; border-bottom: 1px solid rgb(244, 176, 131); border-right: 1px solid rgb(244, 176, 131); padding: 0px 7px;"><p style="text-align:center"><span style=";font-family:'微软雅黑',sans-serif;color:black">利用CP05肽偶联分子可特异性结合CD63的特性，可以将靶向分子或功能分子偶联至外泌体表面，实现靶向性或功能性，交付：载药外泌体及参数检测报告</span></p></td><td width="125" style="border-top: none; border-left: none; border-bottom: 1px solid rgb(244, 176, 131); border-right: 1px solid rgb(244, 176, 131); padding: 0px 7px;"><p style="text-align:center"><span style=";font-family:'微软雅黑',sans-serif;color:black">3</span><span style=";font-family:'微软雅黑',sans-serif;color:black">个工作日</span></p></td></tr><tr><td width="103" style="border-right: 1px solid rgb(244, 176, 131); border-bottom: 1px solid rgb(244, 176, 131); border-left: 1px solid rgb(244, 176, 131); border-image: initial; border-top: none; background: rgb(251, 228, 213); padding: 0px 7px;"><p style="text-align:center"><span style=";font-family:'微软雅黑',sans-serif;color:black">5</span></p></td><td width="255" style="border-top: none; border-left: none; border-bottom: 1px solid rgb(244, 176, 131); border-right: 1px solid rgb(244, 176, 131); background: rgb(251, 228, 213); padding: 0px 7px;"><p style="text-align:center"><span style=";font-family:'微软雅黑',sans-serif;color:black">装载效率检测（NanoFCM）</span></p></td><td width="558" style="border-top: none; border-left: none; border-bottom: 1px solid rgb(244, 176, 131); border-right: 1px solid rgb(244, 176, 131); background: rgb(251, 228, 213); padding: 0px 7px;"><p style="text-align:center"><span style=";font-family:'微软雅黑',sans-serif;color:black">利用纳米流式（NanoFCM）进行膜表面蛋白或者核酸（FITC标记）的阳性率检测来评价药物装载效果，交付：PDF格式样品报告，FCS格式仪器原始数据</span></p></td><td width="125" style="border-top: none; border-left: none; border-bottom: 1px solid rgb(244, 176, 131); border-right: 1px solid rgb(244, 176, 131); background: rgb(251, 228, 213); padding: 0px 7px;"><p style="text-align:center"><span style=";font-family:'微软雅黑',sans-serif;color:black">3</span><span style=";font-family:'微软雅黑',sans-serif;color:black">个工作日</span></p></td></tr><tr><td width="103" style="border-right: 1px solid rgb(244, 176, 131); border-bottom: 1px solid rgb(244, 176, 131); border-left: 1px solid rgb(244, 176, 131); border-image: initial; border-top: none; padding: 0px 7px;"><p style="text-align:center"><span style=";font-family:'微软雅黑',sans-serif;color:black">6</span></p></td><td width="255" style="border-top: none; border-left: none; border-bottom: 1px solid rgb(244, 176, 131); border-right: 1px solid rgb(244, 176, 131); padding: 0px 7px;"><p style="text-align:center"><span style=";font-family:'微软雅黑',sans-serif;color:black">装载效率检测（HPLC）</span></p></td><td width="558" style="border-top: none; border-left: none; border-bottom: 1px solid rgb(244, 176, 131); border-right: 1px solid rgb(244, 176, 131); padding: 0px 7px;"><p style="text-align:center"><span style=";font-family:'微软雅黑',sans-serif;color:black">通过HPLC方法检测外泌体载药效率，交付：DOCX格式报告，PDF格式检测数据</span></p></td><td width="125" style="border-top: none; border-left: none; border-bottom: 1px solid rgb(244, 176, 131); border-right: 1px solid rgb(244, 176, 131); padding: 0px 7px;"><p style="text-align:center"><span style=";font-family:'微软雅黑',sans-serif;color:black">7</span><span style=";font-family:'微软雅黑',sans-serif;color:black">个工作日</span></p></td></tr><tr><td width="103" style="border-right: 1px solid rgb(244, 176, 131); border-bottom: 1px solid rgb(244, 176, 131); border-left: 1px solid rgb(244, 176, 131); border-image: initial; border-top: none; background: rgb(251, 228, 213); padding: 0px 7px;"><p style="text-align:center"><span style=";font-family:'微软雅黑',sans-serif;color:black">7</span></p></td><td width="255" style="border-top: none; border-left: none; border-bottom: 1px solid rgb(244, 176, 131); border-right: 1px solid rgb(244, 176, 131); background: rgb(251, 228, 213); padding: 0px 7px;"><p style="text-align:center"><span style=";font-family:'微软雅黑',sans-serif;color:black">装载效率检测（LC-MS）</span></p></td><td width="558" style="border-top: none; border-left: none; border-bottom: 1px solid rgb(244, 176, 131); border-right: 1px solid rgb(244, 176, 131); background: rgb(251, 228, 213); padding: 0px 7px;"><p style="text-align:center"><span style=";font-family:'微软雅黑',sans-serif;color:black">通过LC-MS方法检测外泌体载药效率，交付：DOCX格式报告，PDF格式检测数据</span></p></td><td width="125" style="border-top: none; border-left: none; border-bottom: 1px solid rgb(244, 176, 131); border-right: 1px solid rgb(244, 176, 131); background: rgb(251, 228, 213); padding: 0px 7px;"><p style="text-align:center"><span style=";font-family:'微软雅黑',sans-serif;color:black">7</span><span style=";font-family:'微软雅黑',sans-serif;color:black">个工作日</span></p></td></tr><tr><td width="103" style="border-right: 1px solid rgb(244, 176, 131); border-bottom: 1px solid rgb(244, 176, 131); border-left: 1px solid rgb(244, 176, 131); border-image: initial; border-top: none; padding: 0px 7px;"><p style="text-align:center"><span style=";font-family:'微软雅黑',sans-serif;color:black">8</span></p></td><td width="255" style="border-top: none; border-left: none; border-bottom: 1px solid rgb(244, 176, 131); border-right: 1px solid rgb(244, 176, 131); padding: 0px 7px;"><p style="text-align:center"><span style=";font-family:'微软雅黑',sans-serif;color:black">细胞改造（慢病毒过表达）</span></p></td><td width="558" style="border-top: none; border-left: none; border-bottom: 1px solid rgb(244, 176, 131); border-right: 1px solid rgb(244, 176, 131); padding: 0px 7px;"><p style="text-align:center"><span style=";font-family:'微软雅黑',sans-serif;color:black">通过转染质粒和转导病毒后，使亲代细胞提高目标核酸或蛋白的表达，交付：外泌体、稳转细胞系、病毒及参数检测报告</span></p></td><td width="125" style="border-top: none; border-left: none; border-bottom: 1px solid rgb(244, 176, 131); border-right: 1px solid rgb(244, 176, 131); padding: 0px 7px;"><p style="text-align:center"><span style=";font-family:'微软雅黑',sans-serif;color:black">20</span><span style=";font-family:'微软雅黑',sans-serif;color:black">个工作日</span></p></td></tr><tr><td width="103" style="border-right: 1px solid rgb(244, 176, 131); border-bottom: 1px solid rgb(244, 176, 131); border-left: 1px solid rgb(244, 176, 131); border-image: initial; border-top: none; background: rgb(251, 228, 213); padding: 0px 7px;"><p style="text-align:center"><span style=";font-family:'微软雅黑',sans-serif;color:black">9</span></p></td><td width="255" style="border-top: none; border-left: none; border-bottom: 1px solid rgb(244, 176, 131); border-right: 1px solid rgb(244, 176, 131); background: rgb(251, 228, 213); padding: 0px 7px;"><p style="text-align:center"><span style=";font-family:'微软雅黑',sans-serif;color:black">细胞改造（慢病毒干扰）</span></p></td><td width="558" style="border-top: none; border-left: none; border-bottom: 1px solid rgb(244, 176, 131); border-right: 1px solid rgb(244, 176, 131); background: rgb(251, 228, 213); padding: 0px 7px;"><p style="text-align:center"><span style=";font-family:'微软雅黑',sans-serif;color:black">通过转染质粒和转导病毒后，使亲代细胞降低目标核酸或蛋白的表达，交付：外泌体、稳转细胞系、病毒及参数检测报告</span></p></td><td width="125" style="border-top: none; border-left: none; border-bottom: 1px solid rgb(244, 176, 131); border-right: 1px solid rgb(244, 176, 131); background: rgb(251, 228, 213); padding: 0px 7px;"><p style="text-align:center"><span style=";font-family:'微软雅黑',sans-serif;color:black">20</span><span style=";font-family:'微软雅黑',sans-serif;color:black">个工作日</span></p></td></tr></tbody></table><p><br/></p></div> <div class="blank30"></div> <div class="blank30"></div> <!--自动调用自定义字段--> <div class="blank20"></div> <div class="blank30"></div> <!-- 投票 --> <script src="/index.php?case=vote&act=view&aid=286"></script> <!-- 自定义表单开始 --> <!-- 自定义表单结束 --> <div class="blank60"></div> <!-- 上下页开始 --> <div id="page"> 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.weixing-txt{position:absolute;top:110px;left:7px;width:100px;margin:0 auto;text-align:center;} .main-im .im_main .go-top{width:50px;height:47px;background:#f5f5f5;border-bottom-right-radius:10px;background:url(/template/D20170425/skin/images/servers/old/totop-icon.png) no-repeat center center;float:right;} .main-im .im_main .go-top a{display:block;width:52px;height:47px;} .main-im .close-im{position:absolute;right:10px;top:-12px;z-index:100;width:24px;height:24px;} .main-im .close-im a{display:block;width:24px;height:24px;background:url(/template/D20170425/skin/images/servers/old/close_im.png) no-repeat left top;} .main-im .close-im a:hover{text-decoration:none;} .main-im .open-im{cursor:pointer; display:block; margin-left:68px;width:40px;height:133px;background:url(/template/D20170425/skin/images/servers/old/open_im.png) no-repeat left top;} </style> <div class="main-im"> <div id="open_im" class="open-im"> </div> <div class="im_main" id="im_main"> <div id="close_im" class="close-im"><a href="javascript:void(0);" title="点击关闭"> </a></div> <a href="http://wpa.qq.com/msgrd?v=3&uin=525274299&site=qq&menu=yes" target="_blank" class="im-qq qq-a" title="在线QQ客服"> <div class="qq-container"></div> <div class="qq-hover-c"><img class="img-qq" src="/template/D20170425/skin/images/servers/old/qq.png"></div> <span> QQ在线咨询</span> </a> <div class="im-tel"> <div>客户咨询热线</div> <div class="tel-num">0592-5792117</div> <!-- <div>公司业务传真</div> <div class="tel-num">0592-5732735</div>--> </div> <div class="im-footer" style="position:relative"> <div class="weixing-container"> <div class="weixing-show"> <div class="weixing-txt">微信扫一扫</div> <img class="weixing-ma" src="/upload/images/201706/14963135840929.jpg"> <div class="weixing-sanjiao"></div> <div class="weixing-sanjiao-big"></div> </div> </div><div class="go-top"><a href="javascript:;" title="返回顶部"></a> </div> <div style="clear:both"></div> </div> </div> </div> <script type="text/javascript" language="javascript"> 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